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Delta Delta4/2/25 13h:47min
MediCalc® | Equations | Renal | Acid-Base | DD Quick Help
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Inputs
Sodium (Na<sup>+</sup>) (S) normal values: 136 - 145 mEq/L Na+ (S)
Chloride (Cl<sup>-</sup>) (S) normal values: 98 - 106 mEq/L Cl- (S)
Bicarbonate (HCO<sub>3</sub><sup>-</sup>) (S) normal values: 21 - 29 mEq/L HCO3- (S)
Anion Gap, desired (AG d) (S) normal values: 8 - 12 mEq/L AG d (S)
HCO3, desired (HCO<sub>3</sub><sup>-</sup> d) (S) normal values: 23 - 25 mEq/L HCO3- d (S)
Outputs
AG (S)
Anion Gap (Serum)
Delta AG (S)
Delta Anion Gap
Delta HCO3 (S)
Delta Bicarbonate
Delta Delta (S) ratio
         
        Equation
AG = Anion Gap (Serum) (S, mEq/L)
Delta AG = Delta Anion Gap (S, mEq/L)
Delta HCO3 = Delta Bicarbonate (S, mEq/L)
DD = Delta Delta (S, ratio)
Na+ = Sodium (S, mEq/L)
Cl- = Chloride (S, mEq/L)
HCO3- = Bicarbonate (S, mEq/L)
AG d = Anion Gap, desired (S, mEq/L)
HCO3- d = HCO3, desired (S, mEq/L)
B= blood. S= serum. P= plasma. U= urine.


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Delta Gap is also called Delta Delta. The change in the anion gap divided by the change in the serum bicarbonate.
Normal values default to HCO3 = 24 mEq/L and Anion Gap = 12 mEq/L.

DD Ratio <1.0 = presence of concurrent non AG metabolic acidosis.
DD Ratio >2.0 = presence of concurrent metabolic alkalosis.



Equation Parameters (Delta Delta)Links to Conversion
PARAMETER 1 Abbrev spcmn Normal Low Normal High Lower Limit Higher Limit C UNITS CF SI UNITS
  Inputs
Sodium Na+ S 136 145 80 200 mEq/L 1 mmol/L
Chloride Cl- S 98 106 50 150 mEq/L 1 mmol/L
Bicarbonate HCO3- S 21 29 0 200 mEq/L 1 mmol/L
Anion Gap, desired AG d S 8 12 8 12 mEq/L 1 mmol/L
HCO3, desired HCO3- d S 23 25 0 50 mEq/L 1 mmol/L
  Outputs
Anion Gap (Serum) AG S 8 16 -100 300 mEq/L 1 mmol/L
Delta Anion Gap Delta AG S 0 4 -50 200 mEq/L 1 mmol/L
Delta Bicarbonate Delta HCO3 S 0 2 -24 100 mEq/L 1 mmol/L
Delta Delta DD S 1 2 -10 50 ratio
About the Parameters: Normal values (and limits) are expressed in C Units. Spcmn = specimen. Abbrev = abbreviation.
CF= conversion factor. Units (c) x CF = Units (si) (unless otherwise specified). Inputs in yellow background, Outputs in blue.
1 Click on the links above to go to Parameter Unit Conversion Pages.


Related Equations
Equations
Renal
Acid-Base
Anion Gap Master (AG mstr)
Anion Gap (Serum) (AG)
Anion Gap 4 (Serum) (AG4_S)
Delta Delta (DD)
Urine Anion Gap (UAG)
Acid Deficit (H_def)
Bicarbonate Deficit (HCO3_def)
Bicarbonate Excess (HCO3_xs)
Chloride Deficit (Cl_def)
Henderson - Hasselbalch Equation (HHE)
Hydrogen ion concentration (from pH) ([H+])
Hydrogen / Potassium Exchange Index (HK_ei)
Hydrogen ion (Acid Base Equation) (H+ ion)
Kassirer-Bleich Equation (KBE)
Lactate Excess (L_xs)
Metabolic Acidosis (Winter) (MetAcid)
Metabolic Alkalosis (MetAlk)
Respiratory Acidosis, acute (RespAcidA)
Respiratory Acidosis, chronic (RespAcidC)
Respiratory Alkalosis, acute (RespAlkA)
Respiratory Alkalosis, chronic (RespALkC)


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  Warning: Physicians and Healthcare Professionals are responsible to employ good clinical judgement in selecting and interpreting Clinical data (inputs, outputs), and to verify all processing (data/knowledge) obtained through the use of Synt®, MediCalc®, iDox®, eH&P™, or any of ScyMed's systems and/or applications. Always double CHECK inputs and computer-generated outputs, data processing and original sources manually.
Normal values presented here are only a general guide. It is essential to check the values established by the specific Laboratory and/or Hospital performing the tests. 		 

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